Accelerating Drug Candidates into ALS

There are drugs that have been tested in humans for other conditions and shown to be safe that could work for ALS, but that have stalled on the way there. Sometimes the barrier was financial, not scientific. This project identifies those compounds, tests them in ALS models, and works to move them into clinical trials. It is the fastest path from a laboratory to a patient. Two drug candidates are currently in testing. Their identity will be revealed as the testing evolves.

Partners:

  • CHOP
  • University of Pennsylvania
  • VIB-UAntwerp

What this project needs:

  • More drug candidates. If you know of a compound with an established safety record and a plausible reason to think it could help in ALS or FTD, we have the infrastructure to evaluate it and move it forward.


Several of these projects require funding, and the project needs for funds fluctuate. To donate to these efforts, please give to an unrestricted fund that is split evenly between End the Legacy and research projects driven towards curing genetic ALS/FTD.